Figure 1

Figure 1: a) Ion selective membrane creates a local ion-depletion zone with high electric field upon applying a voltage, b) Free aptamers and aptamer-protein complex concentrate at different locations on the electric field profile due to their different electrophoretic mobility, c) Optical image of multiplexd PDMS device with 200-µm-wide surface-patterned Nafion thin film on glass substrate. Sample channels and side channels are filled with red and green dyes, respectively. Experimental images are taken at the observation region, d) Multiplexed electrokinetic concentration enhanced aptamer mobility shift assay for detecting IgE in buffer solution.

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    Akintunde Akinwande Anantha Chandrakasan Brian Wardle Carlijn Mulder Carl Thompson Caroline Ross Charles Sodini Chih-Hao Chang CICS Clifton Fonstad Dana Weinstein Dimitri Antoniadis Duane Boning Eugene Fitzgerald Faraz Najafi Francesco Marsili George Barbastathis Hae-Seung Lee Harry Tuller Ichiro Masaki Jason Sussman Jeffrey Lang Jesus del Alamo Jing Kong Joel Dawson Joel Voldman Jongyoon Han Judy Hoyt Karen Gleason Karl Berggren Lan Wei Luca Daniel Luis Velásquez-García Marc Baldo Omar Mysore Philip Reusswig Rajeev Ram Sang-Gook Kim Sangeeta Bhatia Scott Manalis Sean Bishop Tomas Palacios Vitor Manfrinato Vladimir Bulovic Vladimir Stojanovic