Figure 1

Figure 1: A) Experimental schematics. A heating chamber (Olympus) was mounted to the inverted microscope stage. B) The PDMS-glass bonded device consists of the inlet and outlet reservoirs and main channels with triangular pillar arrays. C) Design parameter for red blood cell experiment. Along the flow direction, the inter-pillar spacing was 10 µm. This spacing would allow deformed cells to recover and ready for subsequent deformations. Perpendicular to the flow direction, the pore size varied from 2.5 to 4 µm for different channels.