Hou_bacteria-margination_01

Figure 1: Schematic illustrations of the (A) microfluidic design and (B) separation principle. As blood flows through a narrow microchannel (20 × 20 µm, W×H), deformable RBCs migrate axially to the channel center, resulting in margination of other cell types (bacteria, platelets and leukocytes) towards the channel walls and subsequently removal from the side outlets while the center outlet collects the bacteria-depleted blood.