Discovering potent therapeutics for atherosclerosis requires emulating the natural cellular microenvironment along with relevant blood-flow profiles that regulate disease progression. This talk presents a microfluidic device that overcomes several limitations of current models. It applies programmable spatiotemporal blood flow signatures found in patients directly upon human cells, enabling novel studies on atherogenesis.
Sarvesh Varma holds a Ph.D. and S.M. in Electrical Engineering from MIT, and B.A.Sc (honors) in Nanotechnology Engineering from Univ. of Waterloo. In Prof. Joel Voldman’s group at MIT, his research focused on engineering cell-based sensors and microfluidic systems to study human disease progression.